![]() We examine how undercarboxylated osteocalcin (ucOC) and matrix Gla protein (ucMGP) are converted to carboxylated forms (cOC and cMGP respectively) by K2-7 acting as a cofactor, thus facilitating the deposition of calcium in bones and preventing vascular calcification. ![]() Clinical studies have unequivocally demonstrated the utility of vitamin K2-7 supplementation in ameliorating peripheral neuropathy, reducing bone fracture risk and improving cardiovascular health. Compared to vitamin K1 (phylloquinone), K2-7 is absorbed more readily and is more bioavailable. Vitamin K2-7, also known as menaquinone-7 (MK-7) is a form of vitamin K that has health-beneficial effects in osteoporosis, cardiovascular disease, inflammation, cancer, Alzheimer’s disease, diabetes and peripheral neuropathy. ![]() Nikita Jadhav 1, Saiprasad Ajgaonkar 1, Praful Saha 1, Pranay Gurav 1, Amitkumar Pandey 1, Vivek Basudkar 1, Yash Gada 1, Sangita Panda 1, Shashank Jadhav 2, Dilip Mehta 2 and Sujit Nair 1*
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